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Peptilyze
Longevity & mitochondria

Epitalon studies

113 journal papers mention Epitalon in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.

Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether Epitalon is safe, effective or approved for any use.

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Papers
113
108 articles, 5 reviews
Earliest paper
1990
Most papers in 2004 (11)
Open access
24%
free to read somewhere
Reviews
4%
of all papers listed

What kind of studies

Of 166 papers in PubMed that mention Epitalon in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.

  • Randomized controlled trials5
  • Other clinical trials2
  • Meta-analyses and systematic reviews0
  • Other reviews19
  • Case reports0
  • Animal studies only103
  • Studies in humans59

Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).

Registered clinical studies

Studies on ClinicalTrials.gov that mention Epitalon in their intervention details. A registration says a study is planned or running, not what it found.

Registered
1
Completed
0
Ongoing or planned
1
Phase 1
0
Phase 2
0
Phase 3
0
  1. Systemic and Topical Geroprotective Rejuvenation Assessed by START/REST Aging Clocks

    NCT07888595Enrolling by invitationEarly phase 1started 2026-10-21

The five most recently updated studies. See all 1 on ClinicalTrials.gov. Source: ClinicalTrials.gov (U.S. National Library of Medicine). Studies are found by the compound's name, so a few may be about something else.

Papers per year

1997 to 2026, peak 11 papers in a year. The latest year may still be incomplete.

1997: 2 papers1998: 3 papers1999: 0 papers2000: 4 papers2001: 7 papers2002: 10 papers2003: 8 papers2004: 11 papers2005: 3 papers2006: 3 papers2007: 5 papers2008: 2 papers2009: 0 papers2010: 3 papers2011: 9 papers2012: 3 papers2013: 2 papers2014: 4 papers2015: 2 papers2016: 0 papers2017: 2 papers2018: 0 papers2019: 0 papers2020: 4 papers2021: 1 papers2022: 3 papers2023: 1 papers2024: 2 papers2025: 5 papers2026: 7 papers19972026

Where it is published

  1. Bulletin of Experimental Biology and Medicine42 papers
  2. Advances in Gerontology7 papers
  3. Neuroscience and Behavioral Physiology4 papers
  4. Annals of the New York Academy of Sciences4 papers
  5. International Journal of Molecular Sciences3 papers

The papers

Most citedName in the title

  1. Twenty Years of Study on Effects of Pineal Peptide Preparation: Epithalamin in Experimental Gerontology and Oncology

    Vladimir Nikolaevich Anisimov, Vladimir Kh. Khavinson, Vjacheslav G. Morozov · Annals of the New York Academy of Sciences · 1994

    Review43 citations

  2. Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Promising Properties

    Szymon Kamil Araj, Jakub Brzezik, Katarzyna Mądra-Gackowska et al. · International Journal of Molecular Sciences · 2025

    ReviewOpen access · CC BY10 citationsRead the open copy →

LatestName in title or abstract

  1. Epitalon and Epithalamin: A Narrative Review of Mechanistic, Preclinical, and Clinical Evidence

    Ankur Jain, David M. Gallacher, Mohammed A. Issa et al. · International Journal of Molecular Sciences · 2026

    ReviewOpen access · CC BYRead the open copy →

  2. Therapeutic peptides in gerontology: mechanisms and applications for healthy aging

    Volodymyr Mavrych, Inna Shypilova, Olena Bolgova · Frontiers in Aging · 2026

    ReviewOpen access · CC BY5 citationsRead the open copy →

  3. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

    Omar F. Rahman, Steven J. Lee, William A. Seeds · JAAOS Global Research and Reviews · 2026

    ReviewOpen access · CC BY-NC-ND5 citationsRead the open copy →

  4. Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Promising Properties

    Szymon Kamil Araj, Jakub Brzezik, Katarzyna Mądra-Gackowska et al. · International Journal of Molecular Sciences · 2025

    ReviewOpen access · CC BY10 citationsRead the open copy →

Each list shows up to 40 papers.See all 113 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:26 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.