Ipamorelin studies
54 journal papers mention Ipamorelin in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.
Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether Ipamorelin is safe, effective or approved for any use.
- Papers
- 54
- 48 articles, 6 reviews
- Earliest paper
- 1998
- Most papers in 1998 (11)
- Open access
- 31%
- free to read somewhere
- Reviews
- 11%
- of all papers listed
What kind of studies
Of 51 papers in PubMed that mention Ipamorelin in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.
- Randomized controlled trials2
- Other clinical trials0
- Meta-analyses and systematic reviews0
- Other reviews10
- Case reports0
- Animal studies only20
- Studies in humans25
Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).
Registered clinical studies
Studies on ClinicalTrials.gov that mention Ipamorelin in their intervention details. A registration says a study is planned or running, not what it found.
- Registered
- 3
- Completed
- 2
- Ongoing or planned
- 1
- Phase 1
- 0
- Phase 2
- 2
- Phase 3
- 0
- Trifecta Research Study
NCT07717866Active, not recruitingstarted 2022-08-01
- Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus
NCT00672074CompletedPhase 2started 2008-04
- Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function
NCT01280344CompletedPhase 2started 2011-04
The five most recently updated studies. See all 3 on ClinicalTrials.gov. Source: ClinicalTrials.gov (U.S. National Library of Medicine). Studies are found by the compound's name, so a few may be about something else.
Papers per year
1998 to 2026, peak 11 papers in a year. The latest year may still be incomplete.
Where it is published
- Growth Hormone & IGF Research8 papers
- Gastroenterology7 papers
- European Journal of Medicinal Chemistry4 papers
- The American Journal of Sports Medicine2 papers
- The Journal of Sexual Medicine2 papers
The papers
Most citedName in the title
- The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats
Johan Svensson, Sabrina Lall, Suzanne L. Dickson et al. · Journal of Endocrinology · 2000
Animal studyOpen access29 citationsRead the open copy →
- Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus
Beverley Greenwood–Van Meerveld, Karl R. Tyler, Ehsan Mohammadi et al. · Journal of Experimental Pharmacology · 2012
Open access · CC BY-NC6 citationsRead the open copy →
- Restoring endocrine function in women with premature ovarian insufficiency: A case series on hormonal profile reversal and conception following treatment with Ipamorelin
Joseph Dib MD, Amal Al-Shunnar, Mouna Fawaz et al. · International Journal of Clinical Obstetrics and Gynaecology · 2026
Open accessRead the open copy →
LatestName in title or abstract
- The peptide boom: a critical appraisal of evidence, patient safety risks, and regulatory failure in the experimental wellness peptide market
Giorgi Pkhakadze · Georgian Medical Journal · 2026
Open access · CC BYRead the open copy →
- Peptide Supplements and Their Therapeutic Applications in Sports Medicine
Kushagra Tewari, Timothy P. Liu, Christina Im et al. · The American Journal of Sports Medicine · 2026
Open access · CC BY1 citationsRead the open copy →
- The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Aleksander Dominikowski, Zofia Rękoś, Michał Olejarz et al. · Frontiers in Endocrinology · 2026
ReviewOpen access · CC BY1 citationsRead the open copy →
- Therapeutic peptides in gerontology: mechanisms and applications for healthy aging
Volodymyr Mavrych, Inna Shypilova, Olena Bolgova · Frontiers in Aging · 2026
ReviewOpen access · CC BY5 citationsRead the open copy →
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
Omar F. Rahman, Steven J. Lee, William A. Seeds · JAAOS Global Research and Reviews · 2026
ReviewOpen access · CC BY-NC-ND5 citationsRead the open copy →
- Restoring endocrine function in women with premature ovarian insufficiency: A case series on hormonal profile reversal and conception following treatment with Ipamorelin
Joseph Dib MD, Amal Al-Shunnar, Mouna Fawaz et al. · International Journal of Clinical Obstetrics and Gynaecology · 2026
Open accessRead the open copy →
- Growth Hormone Secretagogues: Between Endocrine Physiology and the Therapeutic Frontier of GH-IGF-1 Axis-Modulating Peptides
Pedro Augusto Zaiats, Pedro Henrique Rodrigues Senteio, Diego Ribeiro et al. · Open Journal of Clinical Diagnostics · 2026
Open access · CC BYRead the open copy →
- (197) Peptides in Practice: Evaluating Efficacy and Safety in Men’s Health
R Arora, Arjun K. Venkatesh, Gene Austin Krishingner et al. · The Journal of Sexual Medicine · 2025
Open accessRead the open copy →
- (349) Therapeutic Peptides in Sexual Medicine: A Narrative Review
E Burchfiel, N Mills, G Saffati et al. · The Journal of Sexual Medicine · 2025
ReviewOpen accessRead the open copy →
- Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics
Ehsan Mohammadi, Tijs Louwies, Claudio Pietra et al. · Journal of Experimental Pharmacology · 2020
Open access · CC BY-NC3 citationsRead the open copy →
- Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males
Deepankar K. Sinha, Adithya Balasubramanian, Alexander J. Tatem et al. · Translational Andrology and Urology · 2020
ReviewOpen access · CC BY-NC-ND11 citationsRead the open copy →
- Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus
Beverley Greenwood–Van Meerveld, Karl R. Tyler, Ehsan Mohammadi et al. · Journal of Experimental Pharmacology · 2012
Open access · CC BY-NC6 citationsRead the open copy →
- Does the Prevalence of Fructose and Lactose Intolerance Differ Between ROME III Subgroups of Functional Dyspepsia (FD) and Irritable Bowel Syndrome (IBS)?
Clive H. Wilder‐Smith, Andrea Materna · Gastroenterology · 2011
Open accessRead the open copy →
- ROME III Functional Dyspepsia (FD) Criteria: Poor Discrimination Between Postprandial Distress Syndrome (PDS) and Epigastric Pain Syndrome (EPS)
Nimish B. Vakil, Katarina Halling, Börje Wernersson et al. · Gastroenterology · 2011
Open access2 citationsRead the open copy →
- Seabream ghrelin: cDNA cloning, genomic organization and promoter studies
Chung-Man Yeung, Chi Bun Chan, Norman Y.S. Woo et al. · Journal of Endocrinology · 2006
Animal studyOpen access55 citationsRead the open copy →
- Growth Hormone (GH) Hypersecretion and GH Receptor Resistance in Streptozotocin Diabetic Mice in Response to a GH Secretagogue
Peter B. Johansen, Yael Segev, Daniel Landau et al. · Journal of Diabetes Research · 2003
Study in humansOpen access · CC BY10 citationsRead the open copy →
- The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats
Johan Svensson, Sabrina Lall, Suzanne L. Dickson et al. · Journal of Endocrinology · 2000
Animal studyOpen access29 citationsRead the open copy →
Each list shows up to 40 papers.See all 54 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:26 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.