Cerebrolysin studies
719 journal papers mention Cerebrolysin in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.
Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether Cerebrolysin is safe, effective or approved for any use.
- Papers
- 719
- 655 articles, 64 reviews
- Earliest paper
- 1979
- Most papers in 2025 (51)
- Open access
- 49%
- free to read somewhere
- Reviews
- 9%
- of all papers listed
What kind of studies
Of 629 papers in PubMed that mention Cerebrolysin in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.
- Randomized controlled trials61
- Other clinical trials28
- Meta-analyses and systematic reviews30
- Other reviews96
- Case reports26
- Animal studies only195
- Studies in humans326
Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).
Registered clinical studies
Studies on ClinicalTrials.gov that mention Cerebrolysin in their intervention details. A registration says a study is planned or running, not what it found.
- Registered
- 43
- Completed
- 19
- Ongoing or planned
- 9
- Phase 1
- 3
- Phase 2
- 11
- Phase 3
- 7
- Combined Acupuncture-Based Therapy for Rehabilitation After Ischemic Stroke
NCT07846488Not yet recruitingstarted 2026-12-01
- Cerebrolysin After Reperfusion in Extended-window EndoVascular Thrombectomy
NCT06339411Not yet recruitingPhase 2started 2026-09-01
- Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness
NCT04427241RecruitingPhase 4started 2023-06-01
- Combined Cerebrolysin and Amantadine Sulfate Administration for Patients With Traumatic Brain Injury in the ICU
NCT06052787CompletedPhase 3started 2023-09-01
- Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy
NCT05821075RecruitingPhase 1 / Phase 2started 2023-08-24
The five most recently updated studies. See all 43 on ClinicalTrials.gov. Source: ClinicalTrials.gov (U.S. National Library of Medicine). Studies are found by the compound's name, so a few may be about something else.
Papers per year
1997 to 2026, peak 51 papers in a year. The latest year may still be incomplete.
Where it is published
- S S Korsakov Journal of Neurology and Psychiatry50 papers
- Alzheimer s & Dementia33 papers
- Journal of Medicine and Life20 papers
- European Neuropsychopharmacology15 papers
- Neuroscience and Behavioral Physiology14 papers
The papers
Most citedName in the title
- Safety and efficacy of Cerebrolysin in early post-stroke recovery: a meta-analysis of nine randomized clinical trials
Natan M. Bornstein, Alla B. Guekht, Johannes Vester et al. · Neurological Sciences · 2017
Meta-analysisOpen access · CC BY114 citationsRead the open copy →
- Cerebrolysin for vascular dementia
Ning Chen, Mi Yang, Jian Guo et al. · Cochrane Database of Systematic Reviews · 2013
Meta-analysisOpen access93 citationsRead the open copy →
- Cerebrolysin for vascular dementia
Shuhui Cui, Ning Chen, Mi Yang et al. · Cochrane Database of Systematic Reviews · 2019
Review65 citations
- Cerebrolysin in the therapy of mild cognitive impairment and dementia due to Alzheimer's disease: 30 years of clinical use
Gavrilova Si, Antón Álvarez · Medicinal Research Reviews · 2020
Review61 citations
- Cerebrolysin for stroke, neurodegeneration, and traumatic brain injury: review of the literature and outcomes
Brian Fiani, Claudia Covarrubias, Amelia Wong et al. · Neurological Sciences · 2021
Review58 citations
- Cerebrolysin in Mild-to-Moderate Alzheimer's Disease: A Meta-Analysis of Randomized Controlled Clinical Trials
Serge G. Gauthier, Jefferson V. Proaño, Jianping Jia et al. · Dementia and Geriatric Cognitive Disorders · 2015
Meta-analysis57 citations
LatestName in title or abstract
- An Adaptive, Time-Informed, Phenotype-Guided Pharmacological Framework for Severe Traumatic Brain Injury : A Hypothesis-Driven Narrative Review
Jae Min Choi, Kwang Wook Jo · Journal of Korean Neurosurgical Society · 2026
ReviewOpen access · CC BY-NCRead the open copy →
- Post-endovascular thrombectomy perfusion imaging (CT and MR) as a prognostic biomarker and patient-selection tool for adjuvant therapy: A systematic review, meta-analysis, and clinical threshold framework
Roni Eichel, Michael Teitcher, Stefan Mausbach et al. · Journal of Stroke and Cerebrovascular Diseases · 2026
Meta-analysisOpen access · CC BYRead the open copy →
- The Efficacy and Safety of Cerebrolysin on Functional Outcomes in Acute Ischemic Stroke: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials (P7-4.011)
Rahman Syed, Ameer Afzal Khan, Anfal Khan et al. · Neurology · 2026
Review
- Therapy prospects for post-stroke aphasia
Anna Nicolaevna Bogolepova · S S Korsakov Journal of Neurology and Psychiatry · 2026
Review
- The effect of Cerebrolysin on the development of skills in patients after acute cerebrovascular accidents
А. А. Шмонин, I.Kh. Kashaev, Е. А. Лучинин et al. · S S Korsakov Journal of Neurology and Psychiatry · 2026
Meta-analysis
- Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Observational Studies
Abdullah Afridi, Fatima Sajjad, Ayesha Arshad et al. · Brain and Behavior · 2026
Meta-analysisOpen access · CC BY2 citationsRead the open copy →
- Neuronutraceuticals for Alzheimer's Disease Treatment: A Systematic Review of Randomised Controlled Trials Over the Last 20 Years
Mehmet Akif Topçuoğlu, Esen Saka · Phytochemicals in Food and Medicine · 2026
ReviewOpen access · CC BYRead the open copy →
- Cerebroprotection in acute ischemic stroke: Perspectives on combining cerebrolysin with recanalization therapy
Marc Ribó, Jacek Staszewski, Steven R. Zeiler et al. · Journal of Stroke and Cerebrovascular Diseases · 2025
ReviewOpen access3 citationsRead the open copy →
Each list shows up to 40 papers.See all 719 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:26 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.