Cerebrolysin studies
719 journal papers mention Cerebrolysin in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.
Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether Cerebrolysin is safe, effective or approved for any use.
- Papers
- 719
- 655 articles, 64 reviews
- Earliest paper
- 1979
- Most papers in 2025 (51)
- Open access
- 49%
- free to read somewhere
- Reviews
- 9%
- of all papers listed
What kind of studies
Of 629 papers in PubMed that mention Cerebrolysin in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.
- Randomized controlled trials61
- Other clinical trials28
- Meta-analyses and systematic reviews30
- Other reviews96
- Case reports26
- Animal studies only195
- Studies in humans326
Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).
Registered clinical studies
Studies on ClinicalTrials.gov that mention Cerebrolysin in their intervention details. A registration says a study is planned or running, not what it found.
- Registered
- 43
- Completed
- 19
- Ongoing or planned
- 9
- Phase 1
- 3
- Phase 2
- 11
- Phase 3
- 7
- Combined Acupuncture-Based Therapy for Rehabilitation After Ischemic Stroke
NCT07846488Not yet recruitingstarted 2026-12-01
- Cerebrolysin After Reperfusion in Extended-window EndoVascular Thrombectomy
NCT06339411Not yet recruitingPhase 2started 2026-09-01
- Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness
NCT04427241RecruitingPhase 4started 2023-06-01
- Combined Cerebrolysin and Amantadine Sulfate Administration for Patients With Traumatic Brain Injury in the ICU
NCT06052787CompletedPhase 3started 2023-09-01
- Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy
NCT05821075RecruitingPhase 1 / Phase 2started 2023-08-24
The five most recently updated studies. See all 43 on ClinicalTrials.gov. Source: ClinicalTrials.gov (U.S. National Library of Medicine). Studies are found by the compound's name, so a few may be about something else.
Papers per year
1997 to 2026, peak 51 papers in a year. The latest year may still be incomplete.
Where it is published
- S S Korsakov Journal of Neurology and Psychiatry50 papers
- Alzheimer s & Dementia33 papers
- Journal of Medicine and Life20 papers
- European Neuropsychopharmacology15 papers
- Neuroscience and Behavioral Physiology14 papers
The papers
Most citedName in the title
- Cerebrolysin enhances neurogenesis in the ischemic brain and improves functional outcome after stroke
Chunling Zhang, Michael Chopp, Yisheng Cui et al. · Journal of Neuroscience Research · 2010
Animal studyOpen access194 citationsRead the open copy →
- Cerebrolysin and Recovery After Stroke (CARS)
Dafin Fior Muresanu, Wolf‐Dieter Heiss, Volker Hoemberg et al. · Stroke · 2015
Randomized trial · Phase 2Open access · CC BY-NC-ND160 citationsRead the open copy →
- Safety and efficacy of Cerebrolysin in early post-stroke recovery: a meta-analysis of nine randomized clinical trials
Natan M. Bornstein, Alla B. Guekht, Johannes Vester et al. · Neurological Sciences · 2017
Meta-analysisOpen access · CC BY114 citationsRead the open copy →
- Cerebrolysin for vascular dementia
Ning Chen, Mi Yang, Jian Guo et al. · Cochrane Database of Systematic Reviews · 2013
Meta-analysisOpen access93 citationsRead the open copy →
- Cerebrolysin combined with rehabilitation promotes motor recovery in patients with severe motor impairment after stroke
Won Hyuk Chang, Chang-Hyun Park, Deog Young Kim et al. · BMC Neurology · 2016
Randomized trial · Phase 4Open access · CC BY78 citationsRead the open copy →
- Cerebrolysin Ameliorates Focal Cerebral Ischemia Injury Through Neuroinflammatory Inhibition via CREB/PGC-1α Pathway
Xin Guan, Yunjie Wang, Guoyin Kai et al. · Frontiers in Pharmacology · 2019
Open access · CC BY70 citationsRead the open copy →
- Efficacy and safety comparison of DL-3-n-butylphthalide and Cerebrolysin: Effects on neurological and behavioral outcomes in acute ischemic stroke
Lixia Xue, Ting Zhang, Yuwu Zhao et al. · Experimental and Therapeutic Medicine · 2016
Open access70 citationsRead the open copy →
- Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury
Yanlu Zhang, Michael Chopp, Yuling Meng et al. · Journal of neurosurgery · 2015
Animal studyOpen access61 citationsRead the open copy →
- Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia
Rubén Antonio Vázquez‐Roque, Brenda Ramos, Carolina Tecuatl et al. · Journal of Neuroscience Research · 2011
Animal studyOpen access61 citationsRead the open copy →
- A Double‐Blind, Placebo‐Controlled, Multicenter Study of Cerebrolysin for Alzheimer's Disease
Chul‐Young Bae, Choo‐Yon Cho, Kyunghee Cho et al. · Journal of the American Geriatrics Society · 2000
Randomized trialOpen access · CC BY-NC-ND61 citationsRead the open copy →
LatestName in title or abstract
- The neuroprotective effect of resveratrol loaded lipid-core nanocapsules and cerebrolysin on midbrain of parkinsonism albino rats model: histological study
Saad Hassouna, M D Safwat, Mohamed Ashmawy et al. · The Egyptian Journal of Histology · 2026
Open access · CC BYRead the open copy →
- An Adaptive, Time-Informed, Phenotype-Guided Pharmacological Framework for Severe Traumatic Brain Injury : A Hypothesis-Driven Narrative Review
Jae Min Choi, Kwang Wook Jo · Journal of Korean Neurosurgical Society · 2026
ReviewOpen access · CC BY-NCRead the open copy →
- The Twenty-First Reported Patient with Complete Remission of the Core Autistic Features: A Child with a Previously Unrecognized Autism–Craniofacial Dysmorphism Syndrome
Aamir Jalal Al-Mosawi · Brain and Neurological Disorders · 2026
Open access · CC BYRead the open copy →
- A comparative clinical and economic advisability of neuroprotective therapy with ethylmethylhydroxypyridine succinate and Cerebrolysin in patients with ischaemic stroke
Evgenia Kochetkova, A. A. Astapovskii, Vladimir N. Drozdov et al. · Neurology neuropsychiatry Psychosomatics · 2026
Open access · CC BYRead the open copy →
- Post-endovascular thrombectomy perfusion imaging (CT and MR) as a prognostic biomarker and patient-selection tool for adjuvant therapy: A systematic review, meta-analysis, and clinical threshold framework
Roni Eichel, Michael Teitcher, Stefan Mausbach et al. · Journal of Stroke and Cerebrovascular Diseases · 2026
Meta-analysisOpen access · CC BYRead the open copy →
- Adjunctive Cerebrolysin therapy following mechanical thrombectomy for tandem right internal carotid artery and middle cerebral artery occlusion with residual post-procedural perfusion deficit: a case report
Natan Meir Bornstein, Roni Eichel, Stefan Mausbach et al. · Journal of Medicine and Life · 2026
Case reportOpen access · CC BYRead the open copy →
- Research-Evidence-Practice Gaps in Post-stroke Neuro-recovery Pharmacological Therapies in Asia
Hou Chang Chiu, Yangchen Yangchen, Dayangku Siti Nur Ashikin Pengiran Tengah et al. · Cerebrovascular Diseases Extra · 2026
Open access · CC BY-NCRead the open copy →
- Cognitive impairments in a comorbid patient: possibilities for correction
Pavel Rudolfovich Kamchatnov, Ekaterina V. Mityaeva, D.T. Chipova et al. · The Clinician · 2026
Open access · CC BYRead the open copy →
- ĐẶC ĐIỂM LÂM SÀNG, HÌNH ẢNH NÃO VÀ KẾT QUẢ ĐIỀU TRỊ HỖ TRỢ CỦA CEREBROLYSIN TRÊN BỆNH NHÂN NHỒI MÁU NÃO CẤP
Tấn Hào Nguyễn, Hữu Phúc Ngô, Văn Minh Lê et al. · Tạp chí Y Dược học Cần Thơ · 2026
Open access · CC BY-NC-SARead the open copy →
- Predictors of Psychoactive and Nootropic Substance Use Among Romanian University Healthcare Students: The Interplay Between Academic Anxiety and Educational Advancement
Ioana-Cezara Caba, Magdalena Iorga, Iustina-Gabriela Mihăianu et al. · Healthcare · 2026
Open access · CC BY1 citationsRead the open copy →
- Improvement of aphasia deficits following traumatic intracranial hemorrhage: a case report
Junhyun Choi · Journal of Medicine and Life · 2026
Case reportOpen access · CC BYRead the open copy →
- Cerebrolysin in neurology and intensive care: new clinical trials and their implications for routine care
Jacek Staszewski, Aleksander Dȩbiec, Bartosz Rustecki et al. · Lekarz Wojskowy · 2026
Open access · CC BY-NC-SARead the open copy →
- IMMEDIATE AND LONG-TERM RESULTS OF THE USE OF NEUROPROTECTIVE DRUGS IN THE TREATMENT OF ISCHEMIC STROKE
Бекбосынов Асхат Жунусович, Javli Sultanov · Ġylym men densaulyķ saķtau. · 2026
Open access · CC BYRead the open copy →
- EFFECTIVENESS OF CEREBROLYSIN IN THE TREATMENT OF ENCEPHALOPATHY IN CHRONIC KIDNEY DISEASE
Dilbar Rakhmatova · Central Asian Journal of Medicine · 2026
Open accessRead the open copy →
- Adjunctive Cerebrolysin therapy following mechanical thrombectomy for acute basilar artery occlusion: a case report
Marina Roje Bedeković, Jerković Ivona, Marijana Bosnar Puretić · Journal of Medicine and Life · 2026
Case reportOpen access · CC BYRead the open copy →
- Cerebrolysin as an adjunct to speech-language therapy in post-stroke Wernicke’s aphasia: a case report
Marina Romano · Journal of Medicine and Life · 2026
Case reportOpen access · CC BYRead the open copy →
- Exosomes Released by Cerebrolysin-Treated Cerebral Endothelial Cells Reverse Fibrin- or tPA-Impaired Endothelial Cell Permeability
Hua Teng, Chao Li, Mingjin Wang et al. · Cells · 2026
Study in humansOpen access · CC BYRead the open copy →
- Biochemical and Pharmacological Studies on Kynurenic Acid Metabolism in the Helix pomatia—Snail Model of Learning and Memory
Halina Baran, Carina Kronsteiner · Biomolecules · 2026
Animal studyOpen access · CC BYRead the open copy →
- Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Observational Studies
Abdullah Afridi, Fatima Sajjad, Ayesha Arshad et al. · Brain and Behavior · 2026
Meta-analysisOpen access · CC BY2 citationsRead the open copy →
- Neuronutraceuticals for Alzheimer's Disease Treatment: A Systematic Review of Randomised Controlled Trials Over the Last 20 Years
Mehmet Akif Topçuoğlu, Esen Saka · Phytochemicals in Food and Medicine · 2026
ReviewOpen access · CC BYRead the open copy →
- Cerebrolysin after Endovascular Thrombectomy in Stroke: 12‑Month Functional Outcomes in a Propensity‑Matched Cohort
Jacek Staszewski, Aleksander Dȩbiec, Katarzyna Agnieszka Gniadek-Olejniczak et al. · Translational Stroke Research · 2026
Study in humansOpen access · CC BY-NC-NDRead the open copy →
- Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: post hoc secondary analysis of the CEREHETIS trial
Калинин Михаил Николаевич, Dina Rustemovna Khasanova · Frontiers in Pharmacology · 2026
Open access · CC BY2 citationsRead the open copy →
- Cerebrolysin and Risk of Hemorrhagic Transformation: A Pooled Analysis of Recent Studies
Bassel Alrabadi, Yousef Alghzawi, Natalie Bandak · Journal of Clinical Neurology · 2026
Open access · CC BY-NCRead the open copy →
- Very Early Short‐Course Cerebrolysin After Tenecteplase and Mechanical Thrombectomy: A Case Report
Hanna Ziąbska, Adam Kobayashi, Michal Adam Karlinski · Case Reports in Neurological Medicine · 2026
Open access · CC BYRead the open copy →
- Cerebrolysin Ameliorates Age-Induced Dendritic Spine Degeneration and Memory Decline in C57BL6 Mice
Leonardo Aguilar‐Hernández, Gabriel D. Flores‐Gómez, Juan Nácher et al. · Neurochemical Research · 2025
Animal studyOpen access · CC BY2 citationsRead the open copy →
- Cerebroprotection in acute ischemic stroke: Perspectives on combining cerebrolysin with recanalization therapy
Marc Ribó, Jacek Staszewski, Steven R. Zeiler et al. · Journal of Stroke and Cerebrovascular Diseases · 2025
ReviewOpen access3 citationsRead the open copy →
- Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis
Philipp Schlager, Ivan Grgac, Guenther Herzer et al. · Frontiers in Neurology · 2025
Open access · CC BY2 citationsRead the open copy →
- The First Documented Case of Joubert Syndrome in Iraq: A Novel Variant
Aamir Jalal Al-Mosawi · Mathews Journal of Pediatrics · 2025
Open access · CC BYRead the open copy →
- Neuroprotective Effects of Cerebrolysin in Moderate Traumatic Brain Injury with Nonoperative Lesions: A 6-Month Prospective Cohort Analysis
Panu Boontoterm, Siraruj Sakoolnamarka, Karanarak Urasyanandana · Asian Journal of Neurosurgery · 2025
Open access · CC BY-NC-NDRead the open copy →
- Autism and Focal Seizures Associated with Left Hemispheric Cortical Atrophy: A Novel Clinical Pattern
Aamir Jalal Al-Mosawi · Mathews Journal of Psychiatry & Mental Health · 2025
Open access · CC BYRead the open copy →
Each list shows up to 40 papers.See all 719 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:26 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.