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Growth hormone axis

Tesamorelin studies

97 journal papers mention Tesamorelin in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.

Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether Tesamorelin is safe, effective or approved for any use.

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Papers
97
82 articles, 15 reviews
Earliest paper
2007
Most papers in 2026 (14)
Open access
58%
free to read somewhere
Reviews
15%
of all papers listed

What kind of studies

Of 95 papers in PubMed that mention Tesamorelin in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.

  • Randomized controlled trials21
  • Other clinical trials2
  • Meta-analyses and systematic reviews3
  • Other reviews33
  • Case reports2
  • Animal studies only1
  • Studies in humans76

Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).

Registered clinical studies

Studies on ClinicalTrials.gov that mention Tesamorelin in their intervention details. A registration says a study is planned or running, not what it found.

Registered
24
Completed
14
Ongoing or planned
3
Phase 1
2
Phase 2
10
Phase 3
2
  1. Body Composition and Adipose Tissue in HIV

    NCT03226821TerminatedPhase 4started 2018-02-07

  2. Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

    NCT06554717RecruitingPhase 2started 2025-07-10

  3. Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study)

    NCT07481734RecruitingPhase 2started 2026-02-02

  4. Phase II Trial of Tesamorelin for Cognition in Aging HIV-Infected Persons

    NCT02572323CompletedPhase 2started 2017-02-15

  5. Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk

    NCT03375788CompletedPhase 2started 2019-01-17

The five most recently updated studies. See all 24 on ClinicalTrials.gov. Source: ClinicalTrials.gov (U.S. National Library of Medicine). Studies are found by the compound's name, so a few may be about something else.

Papers per year

2007 to 2026, peak 14 papers in a year. The latest year may still be incomplete.

2007: 2 papers2008: 3 papers2009: 4 papers2010: 9 papers2011: 13 papers2012: 8 papers2013: 6 papers2014: 4 papers2015: 2 papers2016: 0 papers2017: 5 papers2018: 0 papers2019: 5 papers2020: 5 papers2021: 5 papers2022: 2 papers2023: 2 papers2024: 3 papers2025: 5 papers2026: 14 papers20072026

Where it is published

  1. The Journal of Clinical Endocrinology & Metabolism5 papers
  2. AIDS5 papers
  3. Open Forum Infectious Diseases4 papers
  4. Growth Hormone & IGF Research4 papers
  5. Clinical Infectious Diseases4 papers

The papers

Most citedName in the title

  1. Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials

    A Badran, Abdulrhman Helal, Karim Samir Shata et al. · Obesity Research & Clinical Practice · 2026

    Meta-analysis2 citations

LatestName in title or abstract

  1. Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review

    V Vasylieva, Annette West, Edward Karpman · Sexual Medicine Reviews · 2026

    Review

  2. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration

    Aleksander Dominikowski, Zofia Rękoś, Michał Olejarz et al. · Frontiers in Endocrinology · 2026

    ReviewOpen access · CC BY1 citationsRead the open copy →

  3. Pharmacologic Treatments for the Preservation of Lean Body Mass During Weight Loss

    Gunjan Arora, Katherine R. Conde, Cyrus V Desouza · Journal of Clinical Medicine · 2026

    ReviewOpen access · CC BY7 citationsRead the open copy →

  4. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

    Omar F. Rahman, Steven J. Lee, William A. Seeds · JAAOS Global Research and Reviews · 2026

    ReviewOpen access · CC BY-NC-ND5 citationsRead the open copy →

  5. Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials

    A Badran, Abdulrhman Helal, Karim Samir Shata et al. · Obesity Research & Clinical Practice · 2026

    Meta-analysis2 citations

  6. Efficacy and Safety of Tesamorelin in People Living With HIV (PLWH) With Lipodystrophy: A Systematic Review and Meta-Analysis

    Aqsa Mohammed Ditta, Ruqaiya Muhammad Naeem, Muhammad Mohsin Sami et al. · Journal of the International Association of Providers of AIDS Care (JIAPAC) · 2026

    Meta-analysisOpen access · CC BY-NCRead the open copy →

  7. Metabolic dysfunction-associated steatotic liver disease in people with HIV

    Arijeet K. Gattu, Lindsay T. Fourman · Current Opinion in HIV and AIDS · 2025

    ReviewOpen access9 citationsRead the open copy →

  8. Causes and outcomes of hepatic fibrosis in persons living with HIV

    Debra W. Yen, Kenneth E. Sherman · Current Opinion in HIV and AIDS · 2022

    Review11 citations

  9. Non-Alcoholic Steatohepatitis (NASH) – A Review of a Crowded Clinical Landscape, Driven by a Complex Disease

    Julia M. Fraile, Soumya Palliyil, Caroline Jane Barelle et al. · Drug Design Development and Therapy · 2021

    ReviewOpen access · CC BY-NC152 citationsRead the open copy →

Each list shows up to 40 papers.See all 97 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:26 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.