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Tissue repair

TB-500 studies

25 journal papers mention TB-500 in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.

Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether TB-500 is safe, effective or approved for any use.

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Papers
25
20 articles, 5 reviews
Earliest paper
2017
Most papers in 2026 (14)
Open access
68%
free to read somewhere
Reviews
20%
of all papers listed

What kind of studies

Of 35 papers in PubMed that mention TB-500 in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.

  • Randomized controlled trials0
  • Other clinical trials1
  • Meta-analyses and systematic reviews0
  • Other reviews8
  • Case reports1
  • Animal studies only6
  • Studies in humans23

Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).

Papers per year

2017 to 2026, peak 14 papers in a year. The latest year may still be incomplete.

2017: 1 papers2018: 1 papers2019: 0 papers2020: 2 papers2021: 0 papers2022: 1 papers2023: 0 papers2024: 1 papers2025: 2 papers2026: 14 papers20172026

Where it is published

  1. The American Journal of Sports Medicine2 papers
  2. Water1 papers
  3. Current Pain and Headache Reports1 papers
  4. International Immunopharmacology1 papers
  5. Scientific Reports1 papers

The papers

Most citedName in the title

  1. TB500/TB1000 and SGF1000: A scientific approach for a better understanding of misbranded and adulterated drugs

    Vivian Delcourt, Patrice Garcia, Benjamin Chabot et al. · Drug Testing and Analysis · 2022

    Study in humans6 citations

  2. Investigational Peptides in Orthopaedic Practice: Evidence, Safety, and Patient Counseling for BPC-157, Thymosin Beta-4, and TB-500

    Alexander Tham, Christopher W. Hodgkins, John G. Kennedy · Journal of the American Academy of Orthopaedic Surgeons · 2026

  3. Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study

    Ozancan Biçer, Oktay Adanır, Yiğit Güleryüz et al. · Joint Diseases and Related Surgery · 2026

    Animal studyOpen access · CC BY-NCRead the open copy →

  4. Thymosin Beta-4 and TB-500 in Tissue Healing, Regeneration, and Musculoskeletal Repair: A Scoping Review

    Flynn McGuire, Emma Hughes, Travis G. Maak et al. · Applied Sciences · 2026

    Open access · CC BYRead the open copy →

  5. REGENERATIVE PEPTIDES IN MUSCULOSKELETAL MEDICINE: COMPARATIVE MECHANISMS OF BPC-157, THYMOSIN BETA-4/TB-500, TB-500 FRAGMENT AND KPV IN OSTEOMYOARTICULAR REPAIR

    Luiz Felippe Mendes Caquetti · INTERNATIONAL BLEST SCIENTIFIC · 2026

    Open accessRead the open copy →

  6. Functional Characterization of N -acetyl- l -Leucyl- l -Lysine Supports a Peptide Prodrug Mechanism for TB-500

    Khandoker Asiqur Rahaman, Md Sofequl Islam Mukim, Md Lemon Hasan et al. · Biomaterials Research · 2026

    Open access · CC BYRead the open copy →

  7. "СІРА ЗОНА" ФАРМАКОЛОГІЇ: ОГЛЯД ПЕПТИДНИХ БІОРЕГУЛЯТОРІВ ДЛЯ ВІДНОВЛЕННЯ ПІСЛЯ СПОРТИВНИХ ТРАВМ (BPC-157, TB-500)

    А. В. Чорномидз, М. П. Кланца · Physical Culture and Sport Scientific Perspective · 2025

    Open access · CC BYRead the open copy →

LatestName in title or abstract

  1. Investigational Peptides in Orthopaedic Practice: Evidence, Safety, and Patient Counseling for BPC-157, Thymosin Beta-4, and TB-500

    Alexander Tham, Christopher W. Hodgkins, John G. Kennedy · Journal of the American Academy of Orthopaedic Surgeons · 2026

  2. Regenerative peptides for inferior alveolar nerve injury: a narrative review

    Scott H. Froum, Nathan E. Estrin, Gianna Pico et al. · Frontiers in Dental Medicine · 2026

    ReviewOpen access · CC BYRead the open copy →

  3. Case Report: Regenerative peptides for Inferior alveolar nerve injury: a narrative review with hypothesis-generating three clinical cases

    Scott H. Froum, Nathan E. Estrin, Gianna Pico et al. · Frontiers in Oral Health · 2026

    Case reportOpen access · CC BYRead the open copy →

  4. The peptide boom: a critical appraisal of evidence, patient safety risks, and regulatory failure in the experimental wellness peptide market

    Giorgi Pkhakadze · Georgian Medical Journal · 2026

    Open access · CC BYRead the open copy →

  5. Peptides in Regenerative Medicine: A Comprehensive Review of Clinical Applications in Tissue Repair and Chronic Pain Management

    Choopong Luansritisakul, Monping Chiang, Stacey L. Burns et al. · Current Pain and Headache Reports · 2026

    Review

  6. Peptide Supplements and Their Therapeutic Applications in Sports Medicine

    Kushagra Tewari, Timothy P. Liu, Christina Im et al. · The American Journal of Sports Medicine · 2026

    Open access · CC BY1 citationsRead the open copy →

  7. Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study

    Ozancan Biçer, Oktay Adanır, Yiğit Güleryüz et al. · Joint Diseases and Related Surgery · 2026

    Animal studyOpen access · CC BY-NCRead the open copy →

  8. Thymosin Beta-4 and TB-500 in Tissue Healing, Regeneration, and Musculoskeletal Repair: A Scoping Review

    Flynn McGuire, Emma Hughes, Travis G. Maak et al. · Applied Sciences · 2026

    Open access · CC BYRead the open copy →

  9. Emerging Peptide Therapies in Orthopaedics: Evidence, Safety, and Perioperative Implications

    Ahmed Siddiqi, Khalid Yousuf, Paul B. Jacob · Journal of Orthopaedic Experience & Innovation · 2026

    Open access · CC BY-NC-NDRead the open copy →

  10. REGENERATIVE PEPTIDES IN MUSCULOSKELETAL MEDICINE: COMPARATIVE MECHANISMS OF BPC-157, THYMOSIN BETA-4/TB-500, TB-500 FRAGMENT AND KPV IN OSTEOMYOARTICULAR REPAIR

    Luiz Felippe Mendes Caquetti · INTERNATIONAL BLEST SCIENTIFIC · 2026

    Open accessRead the open copy →

  11. Therapeutic peptides in gerontology: mechanisms and applications for healthy aging

    Volodymyr Mavrych, Inna Shypilova, Olena Bolgova · Frontiers in Aging · 2026

    ReviewOpen access · CC BY5 citationsRead the open copy →

  12. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

    Omar F. Rahman, Steven J. Lee, William A. Seeds · JAAOS Global Research and Reviews · 2026

    ReviewOpen access · CC BY-NC-ND5 citationsRead the open copy →

  13. Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians

    Cory K. Mayfield, Ioanna K. Bolia, Cailan L Feingold et al. · The American Journal of Sports Medicine · 2026

    Review12 citations

  14. Functional Characterization of N -acetyl- l -Leucyl- l -Lysine Supports a Peptide Prodrug Mechanism for TB-500

    Khandoker Asiqur Rahaman, Md Sofequl Islam Mukim, Md Lemon Hasan et al. · Biomaterials Research · 2026

    Open access · CC BYRead the open copy →

  15. "СІРА ЗОНА" ФАРМАКОЛОГІЇ: ОГЛЯД ПЕПТИДНИХ БІОРЕГУЛЯТОРІВ ДЛЯ ВІДНОВЛЕННЯ ПІСЛЯ СПОРТИВНИХ ТРАВМ (BPC-157, TB-500)

    А. В. Чорномидз, М. П. Кланца · Physical Culture and Sport Scientific Perspective · 2025

    Open access · CC BYRead the open copy →

  16. Thymosin β4-derived peptides alleviate neuroinflammation and neurite atrophy in both in vitro models and in vivo 5 × FAD mice: A potential therapy for memory improvement in Alzheimer's disease

    Haiyan Ou, Ruiye Chen, Longjian Zhou et al. · International Immunopharmacology · 2025

    Study in humans1 citations

  17. Novel wellbeing and repair peptide use in the UK: Netnographic findings

    Luke A. Turnock, Evelyn Hearne · Performance Enhancement & Health · 2024

    Open access · CC BY11 citationsRead the open copy →

  18. TB500/TB1000 and SGF1000: A scientific approach for a better understanding of misbranded and adulterated drugs

    Vivian Delcourt, Patrice Garcia, Benjamin Chabot et al. · Drug Testing and Analysis · 2022

    Study in humans6 citations

  19. Logistic regression analysis of environmental and other variables and incidences of tuberculosis in respiratory patients

    Ashutosh Kumar Pathak, Mukesh Sharma, Subodh K Katiyar et al. · Scientific Reports · 2020

    Clinical trialOpen access · CC BY9 citationsRead the open copy →

  20. Evaluating the Performance of a Lab-Scale Water Treatment Plant Using Non-Thermal Plasma Technology

    Stefan Schönekerl, Astrid Weigert, Stephan Uhlig et al. · Water · 2020

    Open access · CC BY12 citationsRead the open copy →

  21. Inactivation Efficacy of a Non-thermal Atmospheric Pressure Plasma Generator against Mycobacterium tuberculosis

    Noori Lee, Sang‐Hee Park, Ji‐Yeon Kim et al. · Korean Journal of Healthcare-Associated Infection Control and Prevention · 2018

    Open access3 citationsRead the open copy →

  22. EFFECT OF HYDROALCOHOLIC EXTRACT OF DRIED FRUITS OF TRAPA NATANS L ON ANIMAL MODELS OF COGNITIVE DYSFUNCTION

    Digambar Balkrishna Ambikar, Niraj Vyawahare · INDIAN DRUGS · 2017

  23. On partial thermoremanent magnetization tail checks in Thellier paleointensity determination

    Yongjae Yu, David J. Dunlop · Journal of Geophysical Research Atmospheres · 2003

    Open access48 citationsRead the open copy →

  24. Elimination of theobromine metabolites in healthy adults

    N. Rodopoulos, L. Höjvall, A. Norman · Scandinavian Journal of Clinical and Laboratory Investigation · 1996

    Study in humans43 citations

  25. Sympathomimetic amines and cardiac arrhythmias

    E Oppenheimer, E. Akavia, S. Shavit et al. · Cardiovascular Research · 1990

    Animal study8 citations

Each list shows up to 40 papers.See all 25 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:31 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.