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Growth hormone axis

Sermorelin studies

20 journal papers mention Sermorelin in the title or abstract. Here are the most cited, the latest, and a few facts about the literature.

Studies range from laboratory work to clinical trials. A paper listed here is not an endorsement and says nothing about whether Sermorelin is safe, effective or approved for any use.

Compare Sermorelin prices, from €22.99 →

Papers
20
15 articles, 5 reviews
Earliest paper
1997
Most papers in 2026 (4)
Open access
45%
free to read somewhere
Reviews
25%
of all papers listed

What kind of studies

Of 25 papers in PubMed that mention Sermorelin in the title or abstract, by the study type PubMed records. Categories overlap, so they do not add up to the total.

  • Randomized controlled trials0
  • Other clinical trials0
  • Meta-analyses and systematic reviews0
  • Other reviews7
  • Case reports1
  • Animal studies only0
  • Studies in humans18

Study types are tags assigned by publishers and PubMed indexers; very new papers are often not tagged yet, and a tag is not a quality rating. Retracted papers are excluded. Source: PubMed (NCBI).

Registered clinical studies

Studies on ClinicalTrials.gov that mention Sermorelin in their intervention details. A registration says a study is planned or running, not what it found.

Registered
27
Completed
21
Ongoing or planned
1
Phase 1
5
Phase 2
7
Phase 3
4
  1. Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

    NCT06554717RecruitingPhase 2started 2025-07-10

  2. Growth Hormone Releasing Hormone Analog to Improve Nonalcoholic Fatty Liver Disease and Associated Cardiovascular Risk

    NCT03375788CompletedPhase 2started 2019-01-17

  3. Adult Growth Hormone Deficiency and Cardiovascular Risk

    NCT00720902TerminatedPhase 4started 2007-02

  4. TH9507 Extension Study in Patients With HIV-Associated Lipodystrophy

    NCT00608023CompletedPhase 3started 2007-08

  5. Tesamorelin Effects on Liver Fat and Histology in HIV

    NCT02196831Completedstarted 2015-07-01

The five most recently updated studies. See all 27 on ClinicalTrials.gov. Source: ClinicalTrials.gov (U.S. National Library of Medicine). Studies are found by the compound's name, so a few may be about something else.

Papers per year

1997 to 2026, peak 4 papers in a year. The latest year may still be incomplete.

1997: 1 papers1998: 2 papers1999: 2 papers2000: 0 papers2001: 0 papers2002: 0 papers2003: 1 papers2004: 1 papers2005: 0 papers2006: 0 papers2007: 1 papers2008: 0 papers2009: 0 papers2010: 0 papers2011: 0 papers2012: 0 papers2013: 0 papers2014: 0 papers2015: 1 papers2016: 1 papers2017: 1 papers2018: 0 papers2019: 0 papers2020: 1 papers2021: 1 papers2022: 0 papers2023: 0 papers2024: 0 papers2025: 2 papers2026: 4 papers19972026

Where it is published

  1. Inpharma Weekly5 papers
  2. The Journal of Sexual Medicine2 papers
  3. Advanced Drug Delivery Reviews1 papers
  4. BioDrugs1 papers
  5. The Journal of Clinical Endocrinology & Metabolism1 papers

The papers

Most citedName in the title

  1. Sermorelin

    Amitabh Prakash, Karen L. Goa · BioDrugs · 1999

    29 citations

  2. A potentially effective drug for patients with recurrent glioma: sermorelin

    Yuanhao Chang, Ruoyu Huang, You Zhai et al. · Annals of Translational Medicine · 2021

    Open access · CC BY-NC-ND7 citationsRead the open copy →

  3. Sermorelin [LAB GHRH],* a peptide analogue of GHRH,** provides considerable benefits in malnourished patients with advanced renal failure,

    &NA; · Inpharma Weekly · 2007

  4. Sermorelin increases IGF-1 level, improves body composition in HIV?

    &NA; · Inpharma Weekly · 2004

  5. Sermorelin

    &NA; · Drugs & Therapy Perspectives · 1999

  6. Sermorelin

    &NA; · Inpharma Weekly · 1998

  7. Sermorelin beneficial in children with growth hormone deficiency

    &NA; · Inpharma Weekly · 1998

  8. Sermorelin: US approval for childhood growth failure

    &NA; · Inpharma Weekly · 1997

LatestName in title or abstract

  1. Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review

    V Vasylieva, Annette West, Edward Karpman · Sexual Medicine Reviews · 2026

    Review

  2. Anterior cervical osteophyte-related dysphagia in a long-term growth hormone user: a case report

    Sui-Ling Perez, Lynette Martinez, Michael Rosselli et al. · Frontiers in Surgery · 2026

    Case reportOpen access · CC BYRead the open copy →

  3. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration

    Aleksander Dominikowski, Zofia Rękoś, Michał Olejarz et al. · Frontiers in Endocrinology · 2026

    ReviewOpen access · CC BY1 citationsRead the open copy →

  4. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

    Omar F. Rahman, Steven J. Lee, William A. Seeds · JAAOS Global Research and Reviews · 2026

    ReviewOpen access · CC BY-NC-ND5 citationsRead the open copy →

  5. (197) Peptides in Practice: Evaluating Efficacy and Safety in Men’s Health

    R Arora, Arjun K. Venkatesh, Gene Austin Krishingner et al. · The Journal of Sexual Medicine · 2025

    Open accessRead the open copy →

  6. (349) Therapeutic Peptides in Sexual Medicine: A Narrative Review

    E Burchfiel, N Mills, G Saffati et al. · The Journal of Sexual Medicine · 2025

    ReviewOpen accessRead the open copy →

  7. A potentially effective drug for patients with recurrent glioma: sermorelin

    Yuanhao Chang, Ruoyu Huang, You Zhai et al. · Annals of Translational Medicine · 2021

    Open access · CC BY-NC-ND7 citationsRead the open copy →

  8. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males

    Deepankar K. Sinha, Adithya Balasubramanian, Alexander J. Tatem et al. · Translational Andrology and Urology · 2020

    ReviewOpen access · CC BY-NC-ND11 citationsRead the open copy →

  9. Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels

    John Tucker Sigalos, Alexander W. Pastuszak, Andrew Allison et al. · American Journal of Men s Health · 2017

    Study in humansOpen access · CC BY-NC3 citationsRead the open copy →

  10. MP76-09 GROWTH HORMONE RELEASING PEPTIDE TREATMENT IN MEN INCREASES SERUM INSULIN-LIKE GROWTH FACTOR-1 LEVELS

    John Tucker Sigalos, Andrew Allison, Alexander W. Pastuszak et al. · The Journal of Urology · 2016

    Open accessRead the open copy →

  11. Operation resistance: A snapshot of falsified antibiotics and biopharmaceutical injectables in Europe

    Bastiaan J. Venhuis, Peter H. J. Keizers, Rüdiger Klausmann et al. · Drug Testing and Analysis · 2015

    Study in humans30 citations

  12. Sermorelin [LAB GHRH],* a peptide analogue of GHRH,** provides considerable benefits in malnourished patients with advanced renal failure,

    &NA; · Inpharma Weekly · 2007

  13. Sermorelin increases IGF-1 level, improves body composition in HIV?

    &NA; · Inpharma Weekly · 2004

  14. PEGylation of growth hormone-releasing hormone (GRF) analogues

    P Esposito · Advanced Drug Delivery Reviews · 2003

    Review76 citations

  15. Sermorelin

    &NA; · Drugs & Therapy Perspectives · 1999

  16. Sermorelin

    Amitabh Prakash, Karen L. Goa · BioDrugs · 1999

    29 citations

  17. Sermorelin

    &NA; · Inpharma Weekly · 1998

  18. Sermorelin beneficial in children with growth hormone deficiency

    &NA; · Inpharma Weekly · 1998

  19. Sermorelin: US approval for childhood growth failure

    &NA; · Inpharma Weekly · 1997

  20. Perinatal Growth Hormone (GH) Physiology: Effect of GH-Releasing Factor on Maternal and Fetal Secretion of Pituitary and Placental GH*

    Francis de Zegher, M Vanderschueren‐Lodeweyckx, Bernard Spitz et al. · The Journal of Clinical Endocrinology & Metabolism · 1990

    Study in humans71 citations

Each list shows up to 40 papers.See all 20 on OpenAlex. Source: OpenAlex (CC0), journal articles and reviews with a DOI, retractions excluded, refreshed weekly, last 4 Nov 2026, 08:26 UTC. Papers are listed by their metadata only; follow the links to read them. A license shown on an open copy is the license the publisher or repository states for that copy.